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For general laboratory use.
Shipping: shipped at ambient temperature
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.Shelf Life: 24 months after date of delivery
Molecular Formula: C10H13N3O6 (free acid)
Molecular Weight: 271.23 g/mol (free acid)
Exact Mass: 271.08 g/mol (free acid)
Purity: ≥ 95 % (HPLC)
Form: solid
Color: white to off-white
Solubility: water, methanol
Spectroscopic Properties: λmax 280 nm, ε 7.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Applications:
Metabolism of dC substituted at position 5[1]
Incorporation into DNA[2]
functional and conformational influence of cytosine modifications[3] -
产品组分
内容 型号 规格 储存温度
5-羧基-dC N1091 5mg -20°C 操作手册
1 常温
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营销中心
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。 -
FAQ
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Selected References:
[1] Schiesser (2013) Deamination, Oxidation, and C-C Bond Cleavage Reactivity of 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxycytosine. J. Am. Chem. Soc. 135:14593.
[2] Schroeder (2014) Synthesis of a DNA promoter segment containing all four epigenetic nucleosides: 5-Methyl-, 5-hydroxymethyl-, 5-formyl-, and 5-carboxy-2'-deoxycytidine. Angew. Chem. Int. Ed. 53: 315.
[3] Sumino (2008) Synthesis and properties of oligodeoxynucleotides containing 5-carboxy-2'-deoxycytidines. Bioorg. Med. Chem. Lett. 18:274.
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