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For general laboratory use.
Please centrifuge briefly before opening (volume ≤2 ml).Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
avoid freeze/thaw cyclesShelf Life: 12 months
Form: liquid (Supplied as serum, preserved in glycerol
Applications:
Anti-human MsrA can be used for Western blot, ELISA and Immunocytochemistry.Description:
Anti-human-MSRB2 (h-Methionine sulfoxide reductase B2) is a rabbit polyclonal antibody that was produced against the recombinant human MsrB2. Methionine sulfoxide reductase B2 (MSRB2) is a mitochondrial enzyme that converts methionine sulfoxide (R) enantiomer back to methionine. This enzyme is suspected of functioning to protect mitochondrial proteins from oxidative damage. Pascual et.al. (2010) report that the retina is one of the human tissues with highest levels of MSRB2 mRNA expression. Other tissues with high expression were heart, kidney and skeletal muscle.Specificity:
Antibody specificity was evaluated by indirect immunofluorescence and western blotting. Western blot of 50 μg protein of the human oral mucosa, parathyroid and thyroid gland revealed in each case the protein band of the 17kDa MsrB2. Anti-MSRB2 is without crossreactivity to the other human proteins or MSRs (MSRA, MSRB1 and MSRB3).
The antibody visualized the MSRB2- immunoreactivity into the cytoplasma of thyroid gland cells (unpublished Fig. A). The nuclei are stained with DAPI (Fig.B). In Fig. C is merged A and B.关键词:- 抗hMSRB2抗体
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产品组分
内容
型号
规格 储存温度
抗hMSRB2抗体
ABD049-01 100ul -20°C 抗hMSRB2抗体
ABD049-02 200ul -20°C 操作手册
1 1 常温室温
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后,按照说明书建议保存于-20°C。 -
FAQ
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Selected References:
Pascual I et al. (2010) Methionine sulfoxide reductase B2 is highly expressed in the retina and protects retinal pigmented epithelium cells from oxidative damage. Exp Eye Res.,90:420. Epub 2009 Dec 22.
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