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For general laboratory use.
Please centrifuge briefly before opening (volume ≤2 ml).Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
avoid freeze/thaw cycles, store in aliquotsShelf Life: 12 months
Form: liquid (Supplied as serum)
Applications:
Indirect Immunofluorescence 1:250. Western Blot 1:500Description:
Polyclonal Antibody pABahPML(460-479)#3 to human PML.Specificity:
Antibody specificity was evalutated by indirect immunoflourescence and western blotting (see Figure 1A and B). The antibody detects all PML isoforms according to Condemine et al. (2006).Immunogen:
The antibody binds to a peptide corresponding to amino acids 460-479 (KGPSYGEDVSNTTTQKRKC) of the human PML protein. No cross reaction with mouse PML protein was observed in Western blots. The immunogen peptide sequence is not conserved in rat, chimpanzee, dog, or bovine PML proteins. -
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内容
型号
规格 储存温度
抗PML抗体
ABD030-01 50ul -20°C 抗PML抗体
ABD030-02 100ul -20°C 操作手册
1 1 常温室温
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。 -
FAQ
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Selected References:
Krejcí et al. (2008) Nuclear organization of PML bodies in leukaemic and multiple myeloma cells. Leukemia Research 32:1866.
Condemine et al. (2006) Characterization of endogenous human promyelocytic leukemia isoforms. Cancer Res. 66:6192.The perinucleolar compartment and the oncogenic super-enhancers are part of the same phase-separated structure filled with phosphatidylinositol 4,5bisphosphate and long noncoding RNA HANR.
Ana Miladinović, Ludovica Antiga, ..., Pavel Hozak
Advances in biological regulation | 2024 Nov 30 | 39648081
Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription
Roberts Ashley P.E., Orr Anne, ..., Boutell Chris
bioRxiv | 2024 Aug 15
Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load
David Marks, Natalie Heinen, ..., Thorsten Müller
Acta Neuropathologica Communications | 2021 Apr 13 | 33849647
HSV-1 oncolytic virus therapies that specifically kill ALT dependent cancers
Clodagh O'Shea, Jason DeHart
us10821141 | 2020 Nov 03
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