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N6-甲基腺苷
别名: N-Methyladenosine, 6-Methyladenosine, NSC-29409, m6A, NSC-29409, N-Methyladenosine, m6A 6-Methyladenosine
CAS 1867-73-8 分子式 C11H15N5O4 分子量 281.27
靶点： Others;
N6-Methyladenosine is a methylated adenine residue. N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological markers for patients with colorectal cancer.
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产品描述 |
N6-Methyladenosine is a methylated adenine residue. N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological markers for patients with colorectal cancer. |
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靶点活性 |
Others, |
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体外活性 |
N6-Methyladenosine is an abundant modification in mRNA and is found within some viruses, and most eukaryotes including mammals, insects, plants and yeast. It is also found in tRNA, rRNA, and small nuclear RNA(snRNA) as well as several long non-coding RNA, such as Xist. [1] [2] [3] N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA). [4] N6-Methyladenosine is a widespread RNA modification in many tissues with high levels in the brain. N6-Methyladenosine is enriched near stop codons and within 3'UTRs in both mouse and human mRNAs. [5] The recent discovery that FTO, an obesity risk gene, encodes an m6A demethylase implicates m6A as an important regulator of physiological processes. [6] |
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体内活性 |
LD50: Mice >1 g/kg (i.g.). [7] |
化学信息
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分子量 |
281.27 |
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分子式 |
C11H15N5O4 |
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CAS |
1867-73-8 |
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溶解度 |
DMSO: 56 mg/mL (199.09 mM) Ethanol: 2 mg/mL (7.11 mM) Water: 14 mg/mL (49.77 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble ) |
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备注 |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
产品组分
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组分内容 |
型号 |
规格 |
储存温度 |
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N6-甲基腺苷 |
T6599-01 |
25mg | -20°C |
| N6-甲基腺苷 | T6599-02 | 50mg | -20°C |
| N6-甲基腺苷 | T6599-03 | 100mg | -20°C |
| N6-甲基腺苷 | T6599-04 | 500mg | -20°C |
| 操作手册 | 1 | 1 |
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