EHMT2 Polyclonal Antibody

EHMT2 Polyclonal Antibody，非常适合做IP, WB实验。更多视频请关注视频号【艾维缔】。哔哩哔哩【IVDSHOW】。抖音【军哥聊表观】。

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免疫生物学

目录号

A-3019

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Application:	IP, WB
Areas of Research:	Histone Methylation & Demethylation
Clonality:	Polyclonal
Conjugate:	Unconjugated
Host:	Rabbit
Isotype:	IgG
Knockout Validated:	Yes
Purification:	Affinity Purified
Reactivity:	Human, Mouse, Rat

Background
EHMT2 (Euchromatic Histone Lysine Methyltransferase 2) is a histone methyltransferase that specifically mono- and dimethylates Lys-9 of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me is a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. This gene also mediates monomethylation of Lys-56 of histone H3 (H3K56me1) in G1 phase, promoting interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates Lys-27 of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Most likely targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of Lys-373 of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.

Description
EHMT2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Mouse, Rat, Human

Isotype
IgG

Uniprot ID
Q96KQ7

Purification
Affinity Purified

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 680-813 of human EHMT2 (NP_006700.3)

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.

Alternative Names
EHMT2; BAT8; C6orf30; G9A; GAT8; KMT1C; NG36; histone-lysine N-methyltransferase EHMT2

Application
WB, IP

产品组分

内容	型号	规格	价格	储存温度
EHMT2 Polyclonal Antibody	A-3019-050	50ul	0.00	-20°C
EHMT2 Polyclonal Antibody	A-3019-100	100ul	0.00	-20°C
操作手册	1	1		常温

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A-3019-EHMT2 Polyclonal Antibody 操作手册

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保存建议厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。
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