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血管内皮生长因子受体2(VEGFR2),也称为激酶插入域受体(KDR),是血管内皮生长因子(VEGF)的一种酪氨酸激酶(TK)受体。表皮生长因子受体(EGFR)过表达是许多癌症类型的常见特征,如乳腺癌和卵巢癌。EGFR激活会导致VEGF表达以及通过VEGFR2进行的信号传导,从而促进血管生成和肿瘤进展。通过小分子、抗体或CAR单独抑制VEGFR2,或与EGFR联合抑制,是癌症免疫治疗中很有前景的治疗策略。
VEGFR2(KDR)激酶检测试剂盒旨在使用Kinase-Glo™ MAX作为检测试剂,测量VEGFR2(KDR)激酶活性,用于筛选和分析应用。该检测试剂盒采用便捷的96孔板格式,包含足够的纯化重组VEGFR2(KDR)激酶(氨基酸805-1356)、激酶底物、ATP和激酶检测缓冲液,可进行100次酶反应。
Assay Kit Format
Luminescent
Species
Human
Target(s)
VEGFR2
UniProt #
P35968
关键词:- VEGFR2(KDR)激酶检测试剂盒
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产品组分
内容 型号
规格 储存温度
VEGFR2(KDR)激酶检测试剂盒
40325-01 96次
-20°C VEGFR2(KDR)激酶检测试剂盒
40325-02 192次
-20°C 操作手册
1 1 常温
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后,按照说明书建议保存于-20°C。 -
FAQ

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References
Sharma, K., et al. Biomed Chromatogr. 2015 Jun; 29(6):803-34.
Fontanella, C., et al. Ann Transl Med. 2014 Dec; 2(12):12
New Design, synthesis, anticancer evaluation, biological screening, and computational study of novel 6,7-dimethoxyquinazoline derivatives as VEGFR-2 inhibitors and apoptotic inducers.
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European journal of medicinal chemistry | 2025 Sep 23 | 41014811
Hybrid nucleobase–heterocycle–2-oxindole scaffolds as innovative cell cycle modulators with potential anticancer activity
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Bioorganic Chemistry | 2025 Jun 30 | 40609278
Anticancer potential of novel benzothiazolyl piperidine-3-carboxamide derivatives as CDKs and VEGFR2 multi-target kinase inhibitors.
Obaid Afzal, Ali Altharawi, ..., Mubarak A Alamri
Journal of Computer-Aided Molecular Design | 2025 Apr 25 | 40278942
Antibacterial and anti-tumor properties of marine posidonoia oceanica leaf extracts
Felemban Athary Abdulhaleem M, Hussein S. Mohamed, ..., Shimaa K. Ali
Journal of Herbs, Spices & Medicinal Plant… | 2025 Mar 17
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