- 产品描述
- 产品组分
- 文件资源
- 营销中心
- 注意事项
- FAQ
- 文献追踪
-
For general laboratory use.
Shipping: shipped at ambient temperature
Storage Conditions: store at 4 °C
Shelf Life: 12 months after date of delivery
Molecular Formula: C18H30N10O3
Molecular Weight: 434.50 g/mol
Exact Mass: 434.25 g/mol
CAS#: 760952-88-3
Purity: ≥ 90 % (HPLC)
Form: solid
Color: off-white to grey
Solubility: water, DMSO, DMF, MeOH
Description:
THPTA is a water-soluble, very effective ligand for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). It serves a dual purpose: 1) Accelaration of the CuAAC reaction by maintaining the Cu(I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction[1,2].THPTA is a superior alternative to water-insoluble TBTA.
A stock solution can be prepared in ddH2O and subsequently be stored at -20°C. Avoid freeze-thaw cycles.
Presolski et al.[1] and Hong et al.[2] provide a general protocol for CuAAC reactions that may be used as a starting point for the set up and optimization of individual assays.
-
产品组分
内容
型号
规格 储存温度
THPTA
CLK1010-01 25mg
-20 °C
THPTA
CLK1010-02 100mg
-20 °C THPTA
CLK1010-03 1g
-20 °C 操作手册
1 1 常温
-
营销中心
-
注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。 -
FAQ
-
Selected References:
[1] Presolski et al. (2011) Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation. Current Protocols in Chemical Biology 3:153.
[2] Hong et al. (2011) Analysis and Optimization of Copper-Catalyzed Azide-Alkyne Cycloaddition for Bioconjugation. Angew. Chem. Int. Ed. 48:9879.ISQ201, a neuroprotective agent in ischemic stroke, is a novel activator of protein synthesis via allosteric binding to translation factor eIF4E.
Emma Martínez-Alonso, Alejandro Escobar-Peso, ..., Alberto Alcázar
International journal of biological macrom… | 2025 Sep 09 | 40935044
Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1
Barbara Orth, Pavel Pohl, ..., Sonja Lorenz
Nature Communications | 2025 Sep 02 | 40897715
Lactulose selectively stimulates members of the gut microbiota, as determined by multi-modal activity-based sorting
Hamid Rasoulimehrabani, Alessandra Riva, ..., David Berry
Gut Microbes | 2025 Jun 27 | 40576010
Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors.
Daniele Musiani, Hatice Yücel, ..., Raphael Ceccaldi
Molecular cell | 2025 Feb 19 | 40010343
Identification of M 4 muscarinic acetylcholine receptor expressing astrocytes that regulate locomotion and survival in murine prion disease
Tejeda Gonzalo S., Molloy Collin, ..., Tobin Andrew B.
bioRxiv | 2025 Jan 29
Targeting n-myristoyltransferases promotes a pan-Mammarenavirus inhibition through the degradation of the Z matrix protein.
Xavier Carnec, Virginie Borges-Cardoso, ..., Sylvain Baize
PLoS pathogens | 2024 Dec 03 | 39625987
Acute multi-level response to defective de novo chromatin assembly in S-phase.
Jan Dreyer, Giulia Ricci, ..., Francesca Mattiroli
Molecular cell | 2024 Nov 05 | 39536749
In vivo DNA replication dynamics unveil aging-dependent replication stress.
Giacomo G Rossetti, Noëlle Dommann, ..., Thanos D Halazonetis
Cell | 2024 Nov 01 | 39293447
Increased Cytotoxicity of Bimetallic Ultrasmall Silver-Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same Size.
Natalie Wolff, Nataniel Białas, ..., Matthias Epple
Materials (Basel, Switzerland) | 2024 Jul 26 | 39124365
Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation
Dominik Kiemel, Ann-Sophie Helene Kroell, ..., Ralf Bartenschlager
Nature communications | 2024 Jul 19 | 39030239
naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation
Francesca Bork, Carsten L Greve, ..., Alexander N R Weber
EMBO Reports | 2024 May 23 | 38783164
Combined Treatment with Host-Directed and Anticytomegaloviral Kinase Inhibitors: Mechanisms, Synergisms and Drug Resistance Barriers.
Markus Wild, Dubravka Karner, ..., Manfred Marschall
Pharmaceutics | 2023 Nov 27 | 38140021
Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery.
Birthe Meineke, Johannes Heimgärtner, ..., Simon J Elsässer
Cell Reports Methods | 2023 Nov 27 | 37935196
Soft-metal(loid)s induce protein aggregation in Escherichia coli
Fabián A. Cornejo, Claudia Muñoz-Villagrán, ..., Felipe A. Arenas
Frontiers in Microbiology | 2023 Nov 22 | 38075883
Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.
Camille Gelot, Marton Tibor Kovacs, ..., Raphael Ceccaldi
Nature | 2023 Sep 18 | 37674080
在线留言
如果您对我们的产品感兴趣，请留下您的信息，我们将尽快与您联系，谢谢！
艾维缔官网
艾德官网
B站IVDSHOW
抖音军哥聊表观
视频号艾维缔
小红书艾维缔
快手表观盒子
表观遗传学
联系我们
