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For general laboratory use.
Shipping: shipped at ambient temperature
Storage Conditions: store at ambient temperature
store dryShelf Life: 12 months after date of delivery
Molecular Formula: C6H7NaO6
Molecular Weight: 198.11 g/mol
CAS#: 134-03-2
Form: solid
Color: white to off-white
Solubility: water
Description:
Na-Ascorbate can be used as a reduction reagent for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC).It catalyzes the reduction of Cu(II) sources such as CuSO4 thereby releasing catalytically reactive Cu(I) ions.
Ideally, solutions should be freshly prepared in ddH2O shortly before use. Alternatively, a stock solution can be prepared, stored at -20°C and freshly by diluted shortly before use.
Please note: Do not use solutions that appear brown. Freshly prepared, fully functional Na-Ascorbate solutions are colorless to slightly yellow and turn brown upon oxidization thereby loosing their reduction capability.
Presolski et al.[1] and Hong et al.[2] provide a general protocol for CuAAC reactions that may be used as a starting point for the set up and optimization of individual assays.
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产品组分
内容
型号
规格 储存温度
抗坏血酸钠
CLKMI005-01 1g
-20 °C
抗坏血酸钠
CLKMI005-02 5g
-20 °C 抗坏血酸钠
CLKMI005-03 10g
-20 °C 操作手册
1 1 常温
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后,按照说明书建议保存于-20°C。 -
FAQ

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Selected References:
[1] Presolski et al. (2011) Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation. Current Protocols in Chemical Biology 3:153.
[2] Hong et al. (2011) Analysis and Optimization of Copper-Catalyzed Azide-Alkyne Cycloaddition for Bioconjugation. Angew. Chem. Int. Ed. 48:9879.Disruption of nucleolar integrity triggers cellular quiescence through organelle rewiring and secretion
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