ApCp

ApCp，AMPCP，Adenosine-5'-[(α,β)-methyleno]diphosphate, Sodium salt，5'-[(α,β)-亚甲基]二磷酸腺苷钠盐。更多视频请关注视频号【艾维缔】。哔哩哔哩【IVDSHOW】。抖音【军哥聊表观】。

关键词

5'-[(α

β)-亚甲基]三磷酸腺苷钠盐

所属分类

IVDEpi

目录号

NU420

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For general laboratory use.

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C₁₁H₁₇N₅O₉P₂ (free acid)

Molecular Weight: 425.23 g/mol (free acid)

Exact Mass: 425.05 g/mol (free acid)

CAS#: 3768-14-7

Purity: ≥ 98 % (HPLC)

Form: solid

Color: white to off-white

Spectroscopic Properties: λ_max 259 nm, ε 15.4 L mmol^-1 cm^-1 (Tris-HCl pH 7.5)

Applications:
X-ray studies with selenophosphate synthetase 1^[1]
Inhibition of ecto phosphodiesterase DPSPX and ecto nucleodidase AMPCP^[2]
Inhibition of 5'-nucleotidase^[3]
Agonistic ligand, mainly for nucleoside receptor A₁
Nucleosidephosphates stabilized against hydrolytic degradation can directly bind to nucleoside receptors.
关键词:
- 5'-[(α
- β)-亚甲基]三磷酸腺苷钠盐

产品组分

内容	型号	规格	储存温度
ApCp	NU420-01	5mg	-20°C
ApCp	NU420-02	25mg	-20°C
操作手册		1	常温

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保存建议厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。
FAQ
Selected References:
[1] Wang et al. (2009) Crystal structures of catalytic intermediates of human selenophosphate synthetase 1. J. Mol. Biol. 390 (4):747.
[2] Chiavegatti et al. (2008) Skeletal muscle expresses the extracellular cyclic AMP-adenosine pathway. Br. J. Pharmacol. 153 (6):1331.
[3] Müller et al. (2008) Inhibition of lipolysis by palmitate, H2O2 and the sulfonylurea drug, glimepiride, in rat adipocytes depends on cAMP degradation by lipid droplets. Biochemistry 47 (5):1259.
Panther et al. (2012) AMP affects intracellular Ca2+ signaling, cytokine secretion and T-cell priming capacity of dendritic cells. PLos One 7 (5):e37560.
Cometti et al. (2003) Oviduct cells express the cyclic AMP-adenosine pathway. Biol. Reprod. 69 (3):868.
Park et al. (1999) Differential effects of adenine nucleotide analogues on shape change and aggregation induced by adnosine 5-diphosphate (ADP) in human platelets. Br. J. Pharmacol. 127 (6):1359.
Ragazzi et al. (1991) Electrophysiological and receptor binding studies to assess activation of the cardiac adenosine receptor by adenine nucleotides. Circulation Res. 68 (4):1035.

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文件下载	文件内容	资源说明
	NU420-ApCp	操作手册
	NU420-ApCp相关单页	宣传单页

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