dApCpp

dApCpp，dAMPCPP，2'-Deoxyadenosine-5'-[(α,β)-methyleno]triphosphate, Sodium salt，2'-脱氧腺苷-5'-[(α,β)-亚甲基]三磷酸钠盐。更多视频请关注视频号【艾维缔】。哔哩哔哩【IVDSHOW】。抖音【军哥聊表观】。

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dApCpp

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IVDEpi

目录号

NU432

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For general laboratory use.

Please centrifuge briefly before opening (volume ≤2 ml).

Shipping: shipped on gel packs

Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Shelf Life: 12 months after date of delivery

Molecular Formula: C₁₁H₁₈N₅O₁₁P₃ (free acid)

Molecular Weight: 489.21 g/mol (free acid)

Exact Mass: 489.02 g/mol (free acid)

CAS#: 138998-91-1

Purity: ≥ 95 % (HPLC)

Form: solution in water

Color: colorless to slightly yellow

Concentration: 10 mM - 11 mM

pH: 7.5 ±0.5

Spectroscopic Properties: λ_max 259 nm, ε 15.4 L mmol^-1 cm^-1 (Tris-HCl pH 7.5)

Applications:
X-ray analysis^{[1, 2]}

Specific Ligands:

DNA-polymerase β^[2]
关键词:
- dApCpp

产品组分

内容	型号	规格	储存温度
dApCpp	NU432-01	50ul(10mM)	-20°C
dApCpp	NU432-02	250ul(10mM)	-20°C
操作手册		1	常温

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NU432-dApCpp
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保存建议厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。
FAQ
Selected References:
[1] Batra et al. (2008) Structure of DNA polymerase β with active-site mismatches suggest a transient abasic site intermediate during misincorporation. Molecular Cell 30:315.
[2] Bakhtina et al. (2009) Contribution of the Reverse Rate of the Conformational Step to Polymerase # Fidelity. Biochemistry 48 (14):3197.
Kirby et al. (2012) Metal-Induced DNA Translocation Leads to DNA Polymerase Conformational Activation. Nucleic Acids Res. 40 (7):2974.
Jiang et al. (2011) Use of Chromophoric Ligands to Visually UNIT 7.15 Screen Co-Crystals of Putative Protein-Nucleic Acid Complexes. Curr. Protoc. Nucleic Acid Chem. 7 (7):15.1
Balbo et al. (2011) Kinetic mechanism of active site assembly and chemical catalysis of DNA polymerase β.Biochemistry 50 (45):9865.

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