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ATP溶液

ATP溶液,ATP - Solution,Adenosine 5'-triphosphate, Sodium salt,5'-三磷酸腺苷钠盐。更多视频请关注视频号【艾维缔】。哔哩哔哩【IVDSHOW】。抖音【军哥聊表观】。


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ATP溶液


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NU1010SOL

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  • For general laboratory use.

    Please centrifuge briefly before opening (volume ≤2 ml).

    Shipping: shipped on gel packs

    Storage Conditions: store at -20 °C

    Shelf Life: 12 months

    Molecular Formula: C10H16N5O13P3 (free acid)

    Molecular Weight: 507.18 g/mol (free acid)

    CAS#: 987-65-5

    Purity: ≥ 99 % (HPLC)

    Form: clear aqueous solution

    Concentration: 100 mM ±2 %

    pH: 8.0 ±0.2 (22 °C)

    Spectroscopic Properties: λmax 259 nm, ε 15.1 L mmol-1 cm-1 (Tris-HCl pH 7.0)

    Applications:
    ATP-sensitive calcium channels[1]
    V-ATPases (cellular proton pumps)[2]
    ATP-coupled chromatin remodelling[3]
    ATP-binding cassette transporters[4]
    ATP-grasp enzymes[5]
    Agonistic ligand, mainly for nucleoside receptor A1
    Nucleoside-triphosphates can be converted by different membrane-bound phosphatases into nucleosides acting as nucleoside receptor ligands.

    Description:
    Ultrapure ATP supplied as clear aqueous solution.

    Specific Ligands:

    Ligand for purinergic receptors:
    P2X1-P2X3[6,7]
    P2X1/4[8]
    P2X4[7]
    P2X7[9,10,11]
    P2X1 - P2X7[12]
    P2Y1[10,14]
    P2Y2[13,14]
    P2Y11[14]

  • 产品组分

    内容

    型号

    规格

    储存温度

    ATP溶液

    NU1010SOL-01

    1ml(100mM)

    -20°C

    ATP溶液

    NU1010SOL-02

    100ml(100mM)

    -20°C

    操作手册

    1 1

    常温

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    NU1010SOL-ATP溶液

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    NU1010SOL-ATP溶液相关单页

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  • 注意事项

    保存建议 厂家推荐蓝冰运输。当您收到产品后,按照说明书建议保存于-20°C。

     

  • FAQ

  • Selected References:
    [1] Wang et al. (2011) The biological effect of endogenous sulfur dioxide in the cardiovascular system. Eur. J. Pharmacol. 670 (1):1.
    [2] Scott et al. (2011) Duelling functions of the V-ATPase. EMBO J. 30 (20):4113.
    [3] Erdel et al. (2011) Chromatin remodelling in mammalian cells by ISWI-type complexes--where, when and why? FEBS J. 278 (19):3608.
    [4] Gatti et al. (2011) Novel insights into targeting ATP-binding cassette transporters for antitumor therapy. Curr. Med. Chem. 18 (27):4237.
    [5] Fawaz et al. (2011) The ATP-grasp enzymes. Bioorg. Chem. 39 (5):185.
    [6] Lambertucci et al. (2015) Medicinal chemistry of P2X receptors: Agonists and orthosteic antagonists. Curr. Med. Chem. 22 (7):915.
    [7] Ralevic (2015) P2X receptors in the cardiovascular system and their potential as therapeutic targets in disease. Curr. Med. Chem. 22 (7):851.
    [8] Harhun et al. (2014) ATP-evoked sustained vasoconstrictions mediated by heteromeric P2X1/4 receptors in cerebral arteries. Stroke 45 (8):2444.
    [9] Facci et al. (2014) Toll-like receptors 2, -3 and -4 prime microglia but not astrocytes across central nervous system regions for ATP-dependent interleukin-1β release. Sci. Rep. 4:6824.
    [10] Stolz et al. (2015) Homodimeric anoctamin-1, but not homodimeric anoctamin-6, is activated by calcium increases mediated by the P2Y1 and P2X7 receptors. Pflugers Archiv DOI:10.1007/s00424-015-1687-3.
    [11] Lord et al. (2014) Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432. J. Pharmacol. Exp. Ther. 351 (3):628.
    [12] Dal Ben et al. (2015) Purinergic P2X receptors: Structural models and analysis of ligand-target interaction. Eur. J. Med. Chem. 89:561.
    [13] Xie et al. (2014) The P2Y2 nucleotide receptor mediates the proliferation and migration of human hepatocellular carcinoma cells induced by ATP. J. Biol. Chem. 289 (27):19137.
    [14] Kim et al. (2002) Methanocarba modification of uracil and adenine nucleotides: High potency of northern ring conformation at P2Y1, P2Y2, P2Y4 and P2Y11 but not P2Y6 receptors. J. Med. Chem. 45:208.
    Volonte et al. (2009) Membrane components and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters. FEBS J. 276:318.
    Yegutkin (2008) Nucleotide and nucleoside converting enzymes: Important modulators of purinergic signalling cascade. Biochim. Biophys. Acta 1783:673.
    Hasko et al. (2007) Shaping of monocyte and macrophage function by adenosine receptors. Pharmacol.& Therapeutics 113:264.
    Holland et al. (1991) Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase. Proc. Natl. Acad. Sci. USA 88 (16):7276.
    Erlich et al. (1988) Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 29 (239):487.
    Williams et al. (1986) Effects of purine nucleotides on the binding of [3H]cyclopentyladenosine to adenosine A1-receptors in rat brain membranes. J. Neurochem. 47 (1):88.
    Sanger et al. (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463.

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    Jana C Albrecht, Timo Reitinger, ..., Elena Conti

    Cell reports  |  2025 Nov 22  |  41275497

    FACT depletion demonstrates a role for nucleosome organization in TAD formation.

    Clemens Mauksch, Yi Zhu, ..., A Marieke Oudelaar

    Molecular systems biology  |  2025 Oct 27  |  41145704 

    Phage-encoded TelN inhibits bacterial Mre11-Rad50 nuclease to protect hairpin telomeres.

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