N端HSP90α格尔德霉素竞争性抑制剂检测试剂盒

N端HSP90α格尔德霉素竞争性抑制剂检测试剂盒，HSP90α (N-Terminal) Geldanamycin Competitive Inhibitor Assay Kit，是一种竞争性荧光偏振（FP）均相检测试剂盒，旨在测量HSP90α（热休克蛋白90α）的N端区域与含有HSP90抑制剂格尔德霉素的荧光探针之间复合物的形成。更多视频请关注视频号【艾维缔】。哔哩哔哩【IVDSHOW】。抖音【军哥聊表观】。

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表观抑制剂筛选

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50298

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内容	型号	规格	储存温度
N端HSP90α格尔德霉素竞争性抑制剂检测试剂盒	50298-01	384次	-20°C
N端HSP90α格尔德霉素竞争性抑制剂检测试剂盒	50298-02	768次	-20°C
操作手册	1	1	常温

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References

Kim J., et al., 2004 Biomol. Screening 9(5): 375-381.

Howes R., et al., 2006 Anal. Biochem. 350:202-213.

Hoter A., et al., 2018 Int J Mol Sci. 19(9):2560.

New Class of Hsp90 C-Terminal Domain Inhibitors with Anti-tumor Properties against Triple-Negative Breast Cancer.

Živa Zajec, Jaka Dernovšek, ..., Tihomir Tomašič

Journal of Medicinal Chemistry  |  2024 Jul 23  |  39042910

The HDAC/HSP90 Inhibitor G570 Attenuated Blue Light-Induced Cell Migration in RPE Cells and Neovascularization in Mice through Decreased VEGF Production

Tai-Ju Hsu, Kunal Nepali, ..., Yu-Wen Cheng

Molecules  |  2021 Jul 19

Ring-opening of five-membered heterocycles conjugated 4-isopropylresorcinol scaffold-based benzamides as HSP90 inhibitors suppressing tumor growth in vitro and in vivo

Yi-Min Liu, Huang-Ju Tu, ..., Jing-Ping Liou

European Journal of Medicinal Chemistry  |  2021 Jul 01  |  33934008

Elaiophylin Is a Potent Hsp90/ Cdc37 Protein Interface Inhibitor with K-Ras Nanocluster Selectivity

Farid A. Siddiqui, Vladimir Vukic, ..., Vladimir N. Uversky

Biomolecules  |  2021 Jun 04  |  34199986

Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling

Farid Ahmad Siddiqui, Hanna Parkkola, ..., Anupama Munshi

Cancers  |  2021 Feb 23  |  33672199

Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells.

Kunal Nepali, Mei-Hsiang Lin, ..., Jing-Ping Liou

Bioorganic Chemistry  |  2020 Oct 21  |  31349117

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression.

Samir Mehndiratta, Mei-Hsiang Lin, ..., Jing-Ping Liou

European Journal of Medicinal Chemistry  |  2020 Feb 18  |  31655430

Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases

Manibarsha Goswami, Kaelyn E. Wilke, Erin E. Carlson

Journal of Medicinal Chemistry  |  2018 Oct 12  |  28933546

  Patent   Methods of treating a metabolic syndrome by modulating heat shock protein (HSP) 90-beta

Niven Rajin Narain, Rangaprasad Sarangarajan, ..., Enxuan Jing

us10023864  |  2018 Jul 17

  Patent   Methods of treating a metabolic syndrome by modulating heat shock protein (HSP) 90-β

Niven Rajin Narain, Rangaprasad Sarangarajan, ..., Enxuan Jing

us09533002  |  2017 Jan 03

Disruption of Heat Shock Protein 90 (Hsp90)-Protein Kinase Cδ (PKCδ) Interaction by (−)-Maackiain Suppresses Histamine H 1 Receptor Gene Transcription in HeLa Cells

Yuki Nariai, Hiroyuki Mizuguchi, ..., Hiroyuki Fukui

The Journal of Biological Chemistry  |  2015 Sep 21  |  26391399

The Quinone Methide Aurin Is a Heat Shock Response Inducer That Causes Proteotoxic Stress and Noxa-dependent Apoptosis in Malignant Melanoma Cells

Angela L. Davis, Shuxi Qiao, ..., Georg T. Wondrak

The Journal of Biological Chemistry  |  2015 Jan 16  |  25477506

Herbimycins D-F, Ansamycin Analogues from Streptomyces sp. RM-7-15

Khaled A Shaaban, Xiachang Wang, ..., Jon S Thorson

Journal of Natural Products  |  2013 Sep 27  |  23947794

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