环丙沙星

环丙沙星，Ciprofloxacin，是一种口服有效的拓扑异构酶 IV 抑制剂。更多视频请关注视频号【艾维缔】。哔哩哔哩【IVDSHOW】。抖音【军哥聊表观】。

关键词

环丙沙星

所属分类

抑制剂

目录号

HY-B0356

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Ciprofloxacin (Bay-09867) 是一种口服有效的拓扑异构酶 IV 抑制剂。Ciprofloxacin 诱导线粒体 DNA 和核 DNA 损伤并导致线粒体功能障碍和活性氧产生。Ciprofloxacin 具有抗增殖活性并诱导细胞凋亡 (apoptosis)。Ciprofloxacin 是一种氟喹诺酮类抗生素，具有强大的抗菌活性。

生物活性	Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity^[1]^[2]^[3]^[4].

分子量	331.34
Formula	C₁₇H₁₈FN₃O₃
CAS 号	85721-33-1
性状	固体
颜色	White to off-white
中文名称	环丙沙星
运输条件	Room temperature in continental US; may vary elsewhere.

产品组分

内容	型号	规格	储存温度
环丙沙星	HY-B0356-01	500mg	-20°C
环丙沙星	HY-B0356-02	1g	-20°C
环丙沙星	HY-B0356-03	5g	-20°C
环丙沙星	HY-B0356-04	10g	-20°C
环丙沙星	HY-B0356-05	50g	-20°C
操作手册	1	1	常温

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保存建议厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。
FAQ
[1]. Tsai WC, et, al. Ciprofloxacin-mediated cell proliferation inhibition and G2/M cell cycle arrest in rat tendon cells. Arthritis Rheum. 2008 Jun;58(6):1657-63.  [Content Brief]

[2]. Steenbergen J, et, al. In Vitro and In Vivo Activity of Omadacycline against Two Biothreat Pathogens, Bacillus anthracis and Yersinia pestis. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02434-16.  [Content Brief]

[3]. Hamblin KA, et, al. Inhaled Liposomal Ciprofloxacin Protects against a Lethal Infection in a Murine Model of Pneumonic Plague. Front Microbiol. 2017 Feb 6;8:91.

[4]. LeMaire SA, et, al. Effect of Ciprofloxacin on Susceptibility to Aortic Dissection and Rupture in Mice. JAMA Surg. 2018 Sep 1;153(9):e181804.  [Content Brief]

  Supplementary   Gut microbiota dysbiosis-mediated ceramides elevation contributes to corticosterone-induced depression by impairing mitochondrial function

Guanhao Wang, Lining Cao, ..., Jianfeng Lu

NPJ Biofilms and Microbiomes  |  2024 Oct 28  |  39468065