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组蛋白存在于真核细胞的染色体中。它们富含精氨酸和赖氨酸，并在进化过程中得到了极大的保守。组蛋白将DNA包装成染色质的紧密团块。每类H2A、H2B、H3和H4的两个核心组蛋白组合起来，被146个碱基对的DNA包裹，形成一个八聚体核糖体。组蛋白尾部经过许多翻译后修饰，直接或间接地改变染色质结构，以促进转录激活或抑制或其他核过程。除了遗传密码外，不同组蛋白修饰的组合显示了所谓的 "组蛋白密码"。组蛋白的甲基化和去甲基化分别由组蛋白甲基转移酶和组蛋白去甲基化酶动态调节。组蛋白H3K9的甲基化与基因压抑有关。
Concentration 1.8 µg/µl Species reactivity Human, mouse，fungi Type Monoclonal Purity Protein A purified Host Mouse Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. DB:Dot blotting WB:Western blot : The quality of antibodies used in this technique is crucial for correct and specific protein identification. ChIP-qPCR (ab) IF:Immunofluorescence: offers huge selection of highly sensitive antibodies validated in IF. CUT&Tag:The quality of antibody used in CUT&Tag is one of the crucial factors for assay success. The antibodies with confirmed high specificity will target only the protein of interest, enabling real results. C -
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组蛋白H3K9三甲基单克隆抗体
C15200146-01
10ug
-20°C 组蛋白H3K9三甲基单克隆抗体
C15200146-02
50ug
-20°C 操作手册
1 1 常温
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保存建议 厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。 -
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Product Citations
High resolution methylation analysis of the HoxA5 regulatory region in different somatic tissues of laboratory mouse during development
Sinha P. et al.Methylation of the Sox9 and Oct4 promoters and its correlation with gene expression during testicular development in the laboratory mouse
Pamnani M et al.Heat shock represses rRNA synthesis by inactivation of TIF-IA and lncRNA-dependent changes in nucleosome positioning
Zhao Z et al.The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability
Salifou K, Ray S, Verrier L, Aguirrebengoa M, Trouche D, Panov KI, Vandromme M
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