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Product Name Cytochalasin D Description Actin polymerization inhibitor
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. Solubility Soluble to 10 mM in ethanol and to 50 mM in DMSO Appearance White Solid Safety Phrases Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R62 - Possible risk of impaired fertility
R68 - Possible risk of irreversible effects
Hazard Phrases:
H300-H361
Precautionary Phrases:
P264-P281-P301 + P310Alternative Names (3S,3aR,4S,6S,6aR,7E,10S,12S,13E,15R,15aR)-3-Benzyl-6-hydroxy-4,10,12-trimethyl-5-methylene-1-oxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate, Zygosporin A Scientific Background Cytochalasin D binds to actin filaments and inhibits their polymerization and elongation, leading to changes in cellular morphology and apoptosis. In neuroscience, it is widely used to study cytoskeletal dynamics, synaptic plasticity, and neuronal migration. Its ability to disrupt actin networks makes it a powerful agent for probing the role of the cytoskeleton in neurodevelopment and neurodegeneration. References 1. Haidle A., and Myers A. (2004) Proc Natl Acad Sci. 101(33): 12048-12053.
2. Ornelles et al., (1986) Mol Cell Biol. 6(5): 1650-1662. -
产品组分
内容
型号
规格 储存温度
细胞松弛素D(Cytochalasin D) SIH-241-01 1mg -20°C 细胞松弛素D(Cytochalasin D) SIH-241-02 5mg -20°C 操作手册
1 1 常温
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。 -
FAQ
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Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes
D. Chan, G. J. Won, ..., J. M. Sivak
Journal of The Royal Society Interface | 2022 Jan 26 | 35078337
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Ramiro López-Medrano, José Manuel Guerra-Laso, ..., Octavio Miguel Rivero-Lezcano
Innate Immunity | 2017 Jun 26 | 27554054
Bleb formation is induced by alkaline but not acidic pH in estrogen receptor silenced breast cancer cells.
Maitham A Khajah, Princy M Mathew, ..., Yunus A Luqmani
International Journal of Oncology | 2016 Mar 21 | 25672508
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