卡那霉素A

卡那霉素A，Kanamycin，CAS No. : 59-01-8，纯度: 99.97%，是一种口服有效的抗菌剂 (革兰氏阴性/阳性细菌)，可通过与 70 S 核糖体亚单位结合，抑制转位并导致编码错误。更多视频请关注视频号【艾维缔】。哔哩哔哩【IVDSHOW】。抖音【军哥聊表观】。

关键词

卡那霉素A

所属分类

抑制剂

目录号

HY-16566

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Kanamycin (Kanamycin A) 是一种口服有效的抗菌剂 (革兰氏阴性/阳性细菌)，可通过与 70 S 核糖体亚单位结合，抑制转位并导致编码错误。Kanamycin 对 M. tuberculosis (敏感或耐药) 以及 K. pneumonia 均具有较好的抑制活性，可用于肺结核和肺炎的研究。

生物活性

Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia^[1]^[2]^[3]^[4].

IC₅₀ & Target

Aminoglycoside

细胞效力
(Cellular Effect)

Cell Line	Type	Value	Description	References
Vero	IC₅₀	>100 μg/mL	Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS-PMS assay	[PMID: 24087924]

体外研究
(In Vitro)

Kanamycin (0.1-100 μg/mL; 2 weeks) exhibits good antibacterial activity (MIC=1-5 μg/mL) to various strains of mycobacteria in vitro^[1].

IVDSHOW has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:	mycobacteria H37Rv, H2, H37RvR-PAS, Ravenel, Kirchbergand and BCG.
Concentration:	0.1-100 μg/mL
Incubation Time:	2 weeks
Result:	Showed good antibacterial activity to various strains of mycobacteria (H37Rv, H2, H37RvR-PAS, Ravenel, and BCG) with MICs were 1 μg/mL and 5 μg/mL for strain of Kirchbergand.

分子量	484.50
Formula	C₁₈H₃₆N₄O₁₁
CAS 号	59-01-8
性状	固体
颜色	White to off-white
中文名称	卡那霉素 A

产品组分

内容	型号	规格	储存温度
卡那霉素A	HY-16566-01	100mg	-20°C
卡那霉素A	HY-16566-02	200mg	-20°C
卡那霉素A	HY-16566-03	500mg	-20°C
卡那霉素A	HY-16566-04	1g	-20°C
卡那霉素A	HY-16566-05	1mLx10mM in DMSO	-20°C
操作手册	1	1	常温