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ROS1 激酶检测试剂盒旨在利用 Kinase-Glo MAX 作为检测试剂，为筛选和特征分析应用测定 ROS1 的活性。该信号可使用能够读取化学发光信号的发光计或微孔板读板机进行检测。
Assay Kit Format
Luminescent
Species
Human
Supplied As
The ROS1 Kinase Assay Kit comes in a convenient 96-well format, with enough purified ROS1, substrate IGF-1Rtide, ATP, and kinase assay buffer for 96 enzyme reactions.
Materials Required But Not Supplied
Kinase-Glo® MAX (Promega #V6073)
Dithiothreitol (DTT; 0.5 M)
Microplate reader capable of reading luminescence
Adjustable micropipettor and sterile tips
30°C incubatorTarget(s)
ROS1
UniProt #
P08922
Stability
This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.
Applications
Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Shipping Temperature
-80°C
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产品组分
内容 型号
规格 储存温度
PDK3激酶检测试剂盒
78286-01 96次
-20°C PDK3激酶检测试剂盒 78286-02 384次
-20°C 操作手册
1 1 常温
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营销中心
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。 -
FAQ
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References
1. Davies, Kurtis D., and Doebele , Robert C.. "Molecular pathways: ROS1 fusion proteins in cancer." Clinical Cancer Research 15 (2013): 4040-4045.
2. Davies, Kurtis D., et al. "Identifying and targeting ROS1 gene fusions in non–small cell lung cancer." Clinical Cancer Research 17 (2012): 4570-4579.
3. Rimkunas, Victoria M., et al. "Analysis of receptor tyrosine kinase ROS1-positive tumors in non–small cell lung cancer: identification of a FIG-ROS1 fusion." Clinical Cancer Research16 (2012): 4449-4457.
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