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二甲基烯丙基焦磷酸与异戊烯焦磷酸发生缩合反应生成牻牛儿基焦磷酸，牻牛儿基焦磷酸再与第二个异戊烯焦磷酸分子发生缩合反应生成法尼基焦磷酸1,2。法尼基化对于多种参与信号转导的蛋白质发挥功能至关重要3,4。
Technical Information
Formal Name
3-
methyl- 2- butenyl- 1- diphosphoric acid, triammonium salt CAS Number
1186-30-7
Synonyms
- Dimethylallyl Pyrophosphate
Molecular Formula
C5H12O7P2 • 3(NH4)
Formula Weight
Formulation(Request formulation change)
A crystalline solid
Solubility
Methanol: 10mM NH4OH (7:3): 2 mg/mlWater: 25 mg/ml
SMILES
[O-]P([O-])(OP([O-])(OC/C=C(C)\C)=O)=O.[NH4+].[NH4+].[NH4+]
InChi Code
InChI=1S/C5H12O7P2.3H3N/c1-5(2)3-4-11-14(9,10)12-13(6,7)8;;;/h3H,4H2,1-2H3,(H,9,10)(H2,6,7,8);3*1H3
InChi Key
VBUNGGIXIOHBHL-UHFFFAOYSA-N
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产品组分
内容
型号
规格 储存温度
DMAPP(ammonium salt) 63180-01 500ug -20°C DMAPP(ammonium salt) 63180-03 1mg -20°C DMAPP(ammonium salt) 63180-04 5mg -20°C DMAPP(ammonium salt) 63180-05 10mg -20°C 操作手册
1 1 常温
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。 -
FAQ
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Product Description References
1. Barnard, G.F., and Popják, G. Human liver prenyltransferase and its characterization. Biochim. Biophys. Acta 661, 87-99 (1981).
2. Laskovics, F.M., and Poulter, C.D. Prenyltransferase: Determination of the binding mechanism and individual kinetic constants for farnesylpyrophosphate synthetase by rapid quench and isotope partitioning experiments. Biochemistry 20, 1893-1901 (1981).
3. Hohl, R.J., Lewis, K.A., Cermak, D.M., et al. Stereochemistry-
dependent inhibition of Ras farnesylation by farnesylphosphonic acids. Lipids 33, 39-46 (1998). 4. Rando, R.R. Chemical biology of protein isoprenylation/methylation. Biochim. Biophys. Acta 1300, 5-16 (1996).
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