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For general laboratory use.
Please centrifuge briefly before opening (volume ≤2 ml).Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.Shelf Life: 12 months after date of delivery
Molecular Formula: C10H15N5O10P2S (free acid)
Molecular Weight: 459.26 g/mol (free acid)
Exact Mass: 459.00 g/mol (free acid)
CAS#: 16541-19-8
Purity: ≥ 95 % (HPLC)
Form: solution in water
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 257 nm, ε 8.8 L mmol-1 cm-1 (Tris-HCl pH 7.5), λmax 342 nm, ε 24.8 L mmol-1 cm-1 (Tris-HCl pH 7.5)
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产品组分
内容
型号
规格 储存温度
6-硫代-鸟苷二磷酸
NU1120-01 50ul(10mM)
-20°C 6-硫代-鸟苷二磷酸
NU1120-02 250ul(10mM)
-20°C 操作手册
1 1 常温
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营销中心
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。 -
FAQ
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Selected References:
Karner et al. (2010) Determination of 6-thioguanosine diphosphate and triphosphate and nucleoside diphosphate kinase activity in erythrocytes: novel targets for thiopurine therapy? Ther. Drug Monit. 32 (2):119.
Weng et al. (1994) Hydrogen bond interactions of G proteins with the guanine ring moiety of guanine nucleotides. Protein Sci. 1:22.Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM.
Nicholas C K Valerie, Kumar Sanjiv, ..., Mikael Altun
Nature Communications | 2024 Dec 06 | 39643609
SERS spectroscopy as a tool for the study of thiopurine drug pharmacokinetics in a model of human B leukemia cells.
Sofia Pagarin, Anna Bolognese, ..., Alois Bonifacio
Chemico-biological interactions | 2023 Dec 25 | 37944627
Supplementary Harmful Effects of the Azathioprine Metabolite 6-Mercaptopurine in Vascular Cells: Induction of Mineralization
Jasmin Prüfer, Mirjam Schuchardt, ..., Yin Tintut
PLoS ONE | 2014 Jul 16 | 25029363
The Magic Spot: A ppGpp Binding Site on E. coli RNA Polymerase Responsible for Regulation of Transcription Initiation
Wilma Ross, Catherine E. Vrentas, ..., Richard L. Gourse
Molecular cell | 2014 May 09 | 23623682
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