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For general laboratory use.
Please centrifuge briefly before opening (volume ≤2 ml).Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.Shelf Life: 12 months after date of delivery
Molecular Formula: C10H15N4O13P3S (free acid)
Molecular Weight: 524.22 g/mol (free acid)
Exact Mass: 523.96 g/mol (free acid)
CAS#: 27652-34-2
Purity: ≥ 95 % (HPLC)
Form: solution in water
Concentration: 10 mM - 11 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 322 nm, ε 27.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Applications:
Competitive inhibitor of T4 RNA ligase[1]
Kinetic parameters with thiopurine methyltransferase[2]
Interaction with (sodium-potassium ion)-dependent ATPase[3]关键词:- 6-巯基嘌呤-核糖苷-5'-三磷酸
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产品组分
内容
型号
规格 储存温度
6-巯基嘌呤-核糖苷-5'-三磷酸
NU1110-01 100ul(10mM)
-20°C 6-巯基嘌呤-核糖苷-5'-三磷酸
NU1110-02 500ul(10mM)
-20°C 操作手册
1 1 常温
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后,按照说明书建议保存于-20°C。 -
FAQ
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Selected References:
[1] Labeikyte et al. (1995) Structural features of nucleotide binding in T4 RNA ligase determined from inhibition by structural analogs of ATP. Biologija 3:13.
[2] Deininger et al. (1994) Purine substrates for human thiopurine methyltransferase. Biochemical Pharmacology 48:2135.
[3] Erdmann et al. (1976) The cardiac glycoside receptor: its properties and its correlation to nucleotide binding sites, phosphointermediate, and Na-K-dependent ATPase activity. Recent Adv. Stud. Cardiac Struct. Metab. 9:329.
Bierau et al. (2007) Pharmacogenetic significance of inosine triphosphatase. Pharmacogenomics 8 (9):1221.
Patzelt et al. (1974) Study of (Na+K)-ATPase with 6-chloropurine triphosphate, 6-mercaptopurine triphosphate and dinitrophenyl-6-thiopurine triphosphate. H-S Z. Physiol. Chem. 355 (10):1237.Discovery of five HIV nucleoside analog reverse-transcriptase inhibitors (NRTIs) as potent inhibitors against the RNA-dependent RNA polymerase (RdRp) of SARS-CoV and 2019-nCoV
Sun Jialei
bioRxiv | 2020 Nov 01
Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.
Barbora Novotná, Lenka Vaneková, ..., Gabriel Birkuš
Journal of Medicinal Chemistry | 2020 Jun 22 | 31715099
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