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N6-(6-氨基己基)-dATP

N6-(6-氨基己基)-dATP,N6-(6-Aminohexyl)-dATP,N6-(6-Aminohexyl)-2'-deoxyadenosine-5'-triphosphate, Sodium salt,N6-(6-氨基己基)-2'-脱氧腺苷-5'-三磷酸,钠盐。更多视频请关注视频号【艾维缔】。哔哩哔哩【IVDSHOW】。抖音【军哥聊表观】。


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N6-(6-氨基己基)-dATP


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目录号

NU835

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  • For general laboratory use.

    Please centrifuge briefly before opening (volume ≤2 ml).

    Shipping: shipped on gel packs

    Storage Conditions: store at -20 °C
    Short term exposure (up to 1 week cumulative) to ambient temperature possible.

    Shelf Life: 12 months after date of delivery

    Molecular Formula: C16H29N6O12P3 (free acid)

    Molecular Weight: 590.36 g/mol (free acid)

    Exact Mass: 590.11 g/mol (free acid)

    CAS#: 106519-33-9

    Purity: ≥ 95 % (HPLC)

    Form: solution in water

    Concentration: 10 mM - 11 mM

    pH: 7.5 ±0.5

    Spectroscopic Properties: λmax 266 nm, ε 16.2 L mmol-1 cm-1 (Tris-HCl pH 7.5)

    Applications:
    Agonistic ligand, mainly for nucleoside receptor A1
    Nucleoside-triphosphates can be converted by different membrane-bound phosphatases into nucleosides acting as nucleoside receptor ligands. In some cases nucleoside phosphates act also directly on nucleoside receptors.

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    型号

    规格

    储存温度

    N6-(6-氨基己基)-dATP

    NU835-01

    30ul(10mM)

    -20°C

    N6-(6-氨基己基)-dATP

    NU835-02

    150ul(10mM)

    -20°C

    操作手册

    1 1

    常温

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    NU835-N6-(6-氨基己基)-dATP

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  • 注意事项

    保存建议 厂家推荐蓝冰运输。当您收到产品后,按照说明书建议保存于-20°C。

     

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  • Selected References:
    Sirci et al. (2012) Ligand-, structure- and pharmacophore-based molecular fingerprints: a case study on adenosine A1, A2A, A2B, and A3 receptor antagonists. J. Comput. Aided Mol. Des. 26:1247.
    Volonte et al. (2009) Membrane components and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters. FEBS J. 276:318.
    Yegutkin (2008) Nucleotide and nucleoside converting enzymes: Important modulators of purinergic signalling cascade. Biochim. Biophys. Acta 1783:673.
    Joshi et al. (2005) Purine derivatives as ligands for A3 adenosine receptors. Current Topics in Medicinal Chemistry 5:1275.
    Hess (2001) Recent advantages in adenosine receptor antagonist research. Expert Opin. Ther. Patents 11 (10):1533.
    Jacobson (2001) Probing adenosine and P2 receptors: design of novel purines and nonpurines as selective ligands. Drug Development Res. 52:178.
    Jacobson et al. (2001) Ribose modified nucleosides and nucleotides as ligands for purine receptors. Nucleosides, Nucleotides & Nucleic Acids 20 (4):333.
    Van Galen et al. (1994) A binding site model and structure-activity relationships for rat A3 adenosine receptor. Molecular Pharmacology 45:1101.
    Gebeyehu et al. (1987) Novel biotinylated nucleotide-analogs for labeling and colorimetric detection of DNA. Nucleic Acids Res. 15:4513.

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