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For general laboratory use.
Please centrifuge briefly before opening (volume ≤2 ml).Shipping: shipped on gel packs
Storage Conditions: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.Shelf Life: 12 months after date of delivery
Molecular Formula: C9H15N2O14P3S (free acid)
Molecular Weight: 500.21 g/mol (free acid)
Exact Mass: 499.95 g/mol (free acid)
CAS#: 35763-29-2
Purity: ≥ 95 % (HPLC)
Form: solution in water
Concentration: 100 mM - 110 mM
pH: 7.5 ±0.5
Spectroscopic Properties: λmax 274 nm, ε 14.2 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Specific Ligands:
Ligand for purinergic receptors:
Potent and selective agonist at P2Y2 receptor and [1,2,3,4]关键词:- 2-硫-UTP
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产品组分
内容
型号
规格 储存温度
2-硫-UTP NU1151XL-01 10ul(100mM) -20°C 2-硫-UTP NU1151XL-02 50ul(100mM) -20°C 2-硫-UTP NU1151XL-03 100ul(100mM) -20°C 操作手册
1 常温
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注意事项
保存建议 厂家推荐蓝冰运输。当您收到产品后,按照说明书建议保存于-20°C。 -
FAQ

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Selected References:
[1] Higgins et al. (2014) Nucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and Monocytes. Mediators Inflamm. 293925.
[2] Zizzo M. et al. (2012) Pharmacological characterization of uracil nucleotide-preferring P2Y receptors modulating intestinal motility: a study on mouse ileum. Purinergic Signal. 8 (2):275.
[3] Ko et al. (2008) Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorg. Med. Chem. 16 (12):6319.
[4] El-Tayeb et al. (2006) Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors. J. Med. Chem. 49 (24):7076.
Kormann et al. (2011) Expression of therapeutic proteins after delivery of chemically modified mRNA in mice. Nature Biotechnology 29:154.
Warren et al. (2010) Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7 (5):618.Transcript-activated collagen matrix as sustained mRNA delivery system for bone regeneration.
Zohreh Sadat Badieyan, Taras Berezhanskyy, ..., Christian Plank
Journal of controlled release : official j… | 2018 Jan 05 | 27586186
cmRNA/lipoplex encapsulation in PLGA microspheres enables transfection via calcium phosphate cement (CPC)/PLGA composites.
Maximilian Utzinger, Anita Jarzebinska, ..., Christian Plank
Journal of controlled release : official j… | 2017 Dec 27 | 28161466
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