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贝伐珠单抗是一种重组人源化免疫球蛋白G1（IgG1）单克隆抗体，可特异性结合所有人类血管内皮生长因子-A（VEGF-A）亚型。这种人源化抗VEGF单克隆抗体已获美国食品药品监督管理局（FDA）批准，与化疗联合作为转移性结直肠癌的一线治疗方案。此前已有研究描述了贝伐珠单抗在多种动物体内的药代动力学特性，这些特性与人源化单克隆抗体的典型特征一致。文献研究表明，维持治疗期间对循环血药浓度的监测是引发部分其他不良反应的直接和/或间接因素。识别与血清浓度相关的（无）疗效生物标志物以及药物不良反应风险因素，并通过可靠方法维持贝伐珠单抗的有效浓度，从而潜在避免部分不良反应，这一举措可能具有重要意义。
Target Bevacizumab Research Area Biologics Reactivity Human Tested Applications ELISA Recommended dilutions Optimal dilutions/concentrations should be determined by the end user. Storage Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. Shelf Life 6 months. Stability The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. Test Range 312.5 ng/ml - 20000 ng/ml Sensitivity < 98.10 ng/ml Standard Form Lyophilized Detection Method Colorimetric Assay Type Competitive Assay Data Quantitative Sample Type Serum and plasma. CAS Number 216974-75-3 Availability Shipped within 10-20 working days. Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.
The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.
Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. -
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贝伐珠单抗ELISA试剂盒 abx395076-01 96次 2-8°C 贝伐珠单抗ELISA试剂盒 abx395076-02 192次 2-8°C 操作手册
1 1 常温
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保存建议 厂家推荐蓝冰运输。当您收到产品后，按照说明书建议保存于-20°C。 -
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